PERSONAL INFORMATION
Date of birth: August 6th, 1985
Nationality: Danish, Russian (dual citizenship)
• EDUCATION
|
2018
2017
2017
2015
2015
2013-2014
2006-2009
2001-2006
|
FELASA A/B/D animal research work course, University of Copenhagen, Denmark
Infectious diseases (5 ECTS, Stanford University, USA)
Strategical management (Copenhagen Business School, Denmark)
Data Analysis and Statistical Inference course (Duke University, USA; studied on-line)
Project Management course (University of California Irvine, USA; studied on-line)
Lecturer Training Programme (University of Southern Denmark (SDU))
Ph. D. (bioorganic chemistry), defended 19.6.2009 at the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences (IBCH RAS), Moscow, Russia; supervisor: Prof. Vladimir Korshun
M. Sc. Degree (Chemistry), defended 2.02.2006 at IBCH RAS and Higher Chemical College of the Russian Academy of Sciences, Moscow, Russia; supervisor: Prof. Vladimir Korshun
|
• CURRENT POSITION(S)
2017-pres. Associate Professor, Department of Chemistry, Technical University of Denmark / Denmark
2018-pres. Founder and CEO, Aptol Pharma ApS, web: www.aptolpharma.com
2023-cur. President, Danish Chemical Society
• PREVIOUS POSITIONS
|
2012-2017
2013-2014
2012-2013
2009-2012
2008-2009
2006-2008
2004-2005
2003-2008
2001-2003
|
Associate Professor, Nucleic Acid Center (NAC), Department of Physics, Chemistry and Pharmacy, University of Southern Denmark / Denmark
Visiting Scholar: Division of Oncology, Ji lab; Shriram Imaging Center, School of Engineering and School of Medicine, Stanford University (SU) / USA
Visiting Professor: Luc Jaeger Lab, University of California Santa Barbara / USA
Postdoctoral Fellow: Jesper Wengel group, NAC SDU / Denmark
Researcher: Oligonucleotide development group (April 2008 – September 2008), Serology diagnostics group of the Laboratory of Postgenomic Technologies (September 2008 – April 2009), Center for Molecular Diagnostics / Moscow / Russia
PhD scholarship / The Sixth Framework Program Marie Curie Host Fellowship for Early-Stage Research Training / University of Southern Denmark / Denmark
Researcher: Proteomics group, Oxford Gene Tech / UK.
Research Fellow: Nucleic Acid Chemistry Lab, IBCH RAS / Moscow / Russia
Research Fellow: Laboratory of Fine Organic Synthesis, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences / Moscow / Russia
|
• SELECTED FELLOWSHIPS AND AWARDS
2019, 2023 Capes research prize / UFMG / Brazil
2018 Jorck research prize /Danish Ministry of Education / Denmark
2013 Carlsberg Elite PostDoc fellowship / Carlsberg Foundation / Denmark
2013 Talent prize / Lundbeck Foundation / Denmark
2012 Elite Research Grant /The Danish Council for Independent Research / Denmark
• SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
|
2021-cur.
2009-2020
|
Currently I supervise 4 PhD students, 1 research assistant and 2 Msc students at the Department of Chemistry, DTU, Denmark
Postdocs: 8; PhD: 4; Master Students: 35
Department of Physics, Chemistry and Pharmacy/University of Southern Denmark (SDU)/Denmark
Department of Chemistry/ DTU / Denmark
|
• TEACHING ACTIVITIES
|
2010-2017.
2017-cur.
|
Lecturer, 3rd semester Organic Chemistry course, SDU, Denmark; 1st semester Chemistry course, / SDU / Denmark; Responsible Professor at the 3rd semester OrganicChemistry Laboratory Course / SDU / Denmark; 3rd semester Analytical Spectroscopy course, SDU, Denmark; establishing a new course “Nucleic Acids in Medicinal Chemistry and Nanobiotechnology/ SDU / Denmark
Lecturer, biomolecular chemistry (5 ECTS, DTU26422)
|
• INSTITUTIONAL RESPONSIBILITIES
2017 Faculty member, DTU / Denmark
2019 Graduate Student Advisor, DTU / Denmark
2019 Member of the Work environment and safety Committee, DTU / Denmark
• SELECTED MAJOR COLLABORATIONS
Prof. A. Cuenda, Bioimaging, National Biotechnology Center, Madrid, Spain; Prof. MD Hanlee Ji and Prof. MD Elizabeth Mellins, Immunology and Cancer research, Stanford School of Medicine and Genome Technology Center, Stanford University, USA; Dr. Kevin Morris, Gene therapy, Beckman Research Institute, City of Hope, CA, USA; Prof. G. Weber, UFMG, Brazil, Prof. N. Habib, IC London, UK.
Industrial collaborations: Novo Nordisk, Polypeptide group, BGI.
• CAREER BREAKS
1.8.2015-30.4.2016 Maternity leave, 8 months
Invited presentations (selected out of more than 100 invited lectures at international meetings)
2022 Astakhova, K. Targeted gene therapy of human diseases. Novo Nordisk / Denmark
2022 Astakhova, K. Novel approaches to molecular diagnostics and gene therapy using oligonucleotide bioconjugates. Freiburg University / Switzerland
2021 Astakhova, K. Peptide conjugates in treatment of human autoimmune diseases, EULAR - keynote speaker / International web conference
2020 Astakhova, K. Ultra-sensitive detection of cancer DNA using LNA/DNA probes. University of Copenhagen / Denmark
2019 Astakhova, K. Towards high throughput synthesis of therapeutic RNA. RNA Consortium meeting, Beckman Research Institute COH / USA
2018 Astakhova, K. Specific detection of autoantibodies in lupus as a new approach for personalized treatment. Keynote speaker, Kenes Autoimmunity Conference / Portugal