May 2025
Welcome to Marta Rosaia. She’s joining the Target-RNA Doctoral Network and will work on discovery of new riboswitch inhibitors.
George and Mads will be in Porto for the midterm meeting of the GlyCanDrug DN.
Marta, Nicolò, and Mads will be in Bergen for the kick-off of the Target-RNA doctoral network.
April 2025
Welcome back to Henri Chédotal! For his postdoctoral studies, Henri will work on development of PROTACs.
March 2025
Mads will be in Lucca for the Glycobiology GRC.
Welcome to Nicolò Mercorelli. He’s joined the Target-RNA Doctoral Network and will work on new types of RNA degraders.
February 2025
A one-and-a-half-year postdoc position is available in our group. The project will involve design and synthesis of PROTACs for mitogen-activated protein kinases (MAPKs). Deadline is February 23. More info here!
Mads is attending the inaugural meeting of the Consortium for iNKT Research and Therapy in Prague. He is presenting recent results from our vaccine research.
Welcome to Dr. Mukul Mahanti, who joins the group for postdoctoral studies. Mukul will work on the SharpSyn project, focusing on rare sugar synthesis.
We are grateful to the DTU Enable Program for supporting our antiviral research with a Discovery grant!
Welcome to Sofus Gamborg, who joins the group for his BSc thesis research.
January 2025
Congratulations to Kasper and Isabella! The work on the ROFF library for fragment-based screening against RNA targets is out in SLAS Discovery. Read the open access article here!
The group was well represented at the 2nd symposium by the Society for Medicinal Chemistry and Chemical Biology. Several posters were presented, and Dileep had a flash presentation.
The annual meeting in the Danish Society for Carbohydrate Chemistry was held at the University of Copenhagen. Great talks by Danish carbohydrate chemist and our invited speaker, Prof. Matthieu Sollogoub. At the event, Mads was presented with the prize for “Carbohydrate Chemist of the Year, 2024” – he is very honored and grateful to the society for the award.
Mads was in Clearwater Beach, FL, presenting our work on fluorinated fragment libraries for screening protein and RNA targets. The 3F and ROFF research was well received at the ACS Winter Fluorine Conference.
We are recruiting for INTERACT – opportunities to join exciting interdisciplinary projects at DTU and the University of Copenhagen. Deadline February 20, 2025. The following opportunities are available in our group:
Project 5: Hosted at BRIC, a collaboration with Professor Jesper Bøje Andersen. We will search for new PPI inhibitors relevant to bile duct cancers.
Project 17: Hosted at DTU, a collaboration with Professor Anders H. Lund. We will identify new small molecule ligands for oncoribosomes.
Project 18: Hosted at DTU, a collaboration with Professor Krister Wennerberg. We will investigate vaccine technologies in advanced cancer cell models.
Read more and apply here!
December 2024
We are grateful to the Novo Nordisk Foundation for supporting our vaccine program. Mads is extremely happy to be named a Distinguished Innovator and join the ranks of investigators championing technologies that aim to benefit society. Stay tuned for opportunities to join our program in the coming years.
Our intranasal vaccine technology is highlighted in DTU's research magasine DYNAMO. Read the article in Danish here!
Congratulations to Rebekka, who is the winner of the 2024 Clausen lab bake-off!
October 2024
Congratulations to Viola! Our collaboration with the Ding group at DTU Bioengineering is out in Nat. Commun. Alligamycin A is a new antifungal natural product isolated from a Streptomyces strain.
September 2024
We are recruiting a postdoc in organic synthesis and carbohydrate chemistry. Deadline is October 15. Read more and apply here!
Congratulations to Peng! Our article describing a polysaccharide vaccine for S. Pneumonia is out in Commun. Biol. Thanks to all co-authors for a great collaboration. Read the open access article here!
August 2024
Welcome to Román Sainz! He joins the group as a postdoc in collaboration with the Gotfredsen group and NMR Center DTU. He will work on FBDD and RNA targeting.
We have two openings for PhD positions as part of the TargetRNA doctoral network. See all the positions here and the specific positions in the groups here: DC2 and DC3. There is a mobility requirement for the positions – apply before September 15 through JobNorge.
Mads was visiting BOKU in Vienna, presenting recent results from the group. It was a pleasure to catch up with Prof. Fabian Pfrengle and discuss ongoing scientific projects with members of his team!
July 2024
Congratulations to Cecilia et al. Our cancer vaccine technology is finally out in RSC Med. Chem. Great collaboration with Croda Pharma, the Goletz group at DTU Bioengineering, and DTU Health Technology. Read the open access article here!
Congratulations to Cecilia! Our collaboration with the Pfrengle group at BOKU on GT arrays is out in Chem. Comm. Cecilia’s RG-I backbone heptasaccharide played a key role in characterizing a plant rhamnosyl transferase – stay tuned for the exciting chemistry, soon to appear on ChemRxiv!
June 2024
We are grateful to the European Commission for supporting the COFUND program INTERdisciplinary MSCA ACTion for HEALTH (INTERACT). We look forward to the collaboration with the University of Copenhagen and to bridge technical, basic, and clinical science
We are grateful to the Novo Nordisk Foundation for supporting the application SHARPSYN - Sharpening synthetic chemical tools by targeting Nature’s most complex glycan through the NERD program. The grant will allow us to supercharge our activities in synthetic method development, oligosaccharide synthesis, and plant cell wall biology. Look out for positions announced over the coming months and years.
Welcome to Natalia Skinder. She joins the group as a postdoctoral fellow, working on our carbohydrate-based vaccine technologies.
George and Mads were in Zaragoza for the first conference of the GlyCanDrug network.
Cláudia and Mads were in Oxford for the annual general assembly of the Fragment-Screen project.
Mads will be in Miami, visiting project partners in the TNFR project.
May 2024
Welcome to George Lasisi. He joins the group for his PhD with in the GlyCanDrug doctoral network. He will work on the identification of inhibitors of glycosyl transferases.
Mads will present our vaccine technology for infectious disease at the DTU Microbes Initiative Conference 2024.
Mads will share recent results from the group at the Spring symposium of the Center for Medicinal Chemistry at the University of Copenhagen on May 30. See the full program here.
April 2024
Mads will be in Berlin for the kickoff of the IMPULSE project. We look forward to the collaboration with EU-OPENSCREEN ERIC and the Brenk group at the University of Bergen on new technologies.
We are grateful to the European Commission for the invitation to initiate grant agreement negotiations for the TargetRNA project. We look forward to collaborating with the University of Bergen, Goethe University Frankfurt and the other partners.
March 2024
Kasper successfully defended his PhD on March 22. Thanks to the committee: Prof. Teresa Carlomagno, Prof. Anders Bach, and Assoc. Prof. Sebastian Meier for an inspiring discussion of the thesis.
The 2024 bakeoff is underway.
Welcome to Rebekka Riis. She joins the group for her PhD in collaboration with Prof. Jan Ardenkjær-Larsen at DTU Healthtech. Rebekka will be working on synthesis of radical enhancers for Hyperpolarized Magnetic Resonance.
We are grateful to the DTU PoC fund for their continued belief in our epilepsy project. We look forward to continue the pursuit of better treatment options.
February 2024
Welcome to Yevhenii Sokolenko. He joins the group as a postdoc working on PROTAC development.
Welcome to Yann Duchesne, who joins the group for his MSc thesis project. He will work with Cláudia in the FBDD team.
Welcome to Jimmy Liang, who joins the group for his BSc thesis research.
January 2024
We are recruiting a postdoc in vaccine development, immunology, and cell biology. Deadline is February 15. Read more and apply here!
Drug Discovery Today has a feature on a decade of achievements by the European Lead Factory. We are proud of our contributions to the design and synthesis of the academic compound library in ELF.
The group will be well represented at the Torkil Holm Symposium 2024.
Welcome back to Ahmad Haidar. He joins the group for his PhD studies in collaboration with Prof. Jan Ardenkjær-Larsen at DTU Healthtech. Ahmad will be working on synthesis of enhancers for Hyperpolarized Magnetic Resonance.
The 2nd meeting in the Danish Society for Carbohydrate Chemistry took place in Aarhus on January 18. Thanks to all the participants for a great meeting – and a special thanks to Carmen Galan, who shared recent results from her lab in Bristol.
Congratulation to Cecilia, who was awarded the prize for best talk by an early-stage researcher!
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