Enzymatic reaction in organic solvent

Organic solvents are widely appreciated as reaction media for enzyme catalysis. The solvent has profound effects on several reaction parameters, such as enzymatic activity & kinetics, enzyme specificity, and stability & thermostability. This has important implications, since specificity can be a key property in biocatalysis.

We are particularly interested in:

• To study organic solvent effects on enzyme function.
• To investigate if solvent effects on protein properties can explain medium effects on experimentally determined activity  specificity.